 |
                |
|
|
 |
 |
 |
|
|
Mangosteen References
Mangosteen is composed of these substances:
There is a big buzz in the medical and holistic community these days and it’s all because of a fairly recent discovery. This discovery is the phenomenal health benefits the human body derives from a phytochemical class known as xanthones. Over 200 xanthones have been identified in nature, with each one possessing its own unique effects on the body. Xanthones are contained within a large family of compounds known as phenols and within this grouping can also found bioflavonoids, anthocyanins and proanthocyanidins (OPCs).
Xanthones are the primary active phytochemical class found in the Mangosteen fruit (Garcinia mangostana L.). Science has crowned the king of xanthones and it's the mangosteen fruit, with over 40 xanthones identified in the pericarp, more commonly known as the rind, making the mangosteen the most abundant xanthones source in the world. Of these 40 or so xanthones only six of the xanthones have been studied in depth, with much excitement I would like to add.
These xanthones isolated are Mangostin, Mangostanol, y-Mangostin, Gartanin, Garcinone B and Garcinone E. Researches still don't completely understand how the xanthones in the mangosteen fruit exert such a favorable impact on human health. Researches though, do validate the fact that the mangosteen possesses powerful healing properties that surpass many man made substances.
|
Mangosteen Fruit (Garcinia Mangostana)
With the accumulated knowledge of ancient Asian medicine, which was passed on to European explorers and settlers, it's no wonder that so much modern research has been conducted on the Mangosteen and its beneficial properties. An enormous amount of modern study and research has been channeled toward unlocking the secrets of this remarkable fruit. |
 |
In fact, scientists have actually identified the major compounds found in the Mangosteen that are responsible for its healthful characteristics. These days, everybody knows about free radicals and antioxidants. Free radicals attack the cells in our bodies every second of every day, and antioxidants work to the repair the damage. Much has been made of the extensive antioxidant properties of vitamins, especially Vitamin C and Vitamin E.
But did you know that there exists an antioxidant that is even more powerful than any vitamin? This powerful, life-enhancing substance is called Xanthone.
In fact, there is a whole family of Xanthones, and the most dynamic of these are found in the amazing whole fruit Mangosteen. While most people know about the antioxidant benefits of Vitamins C and E, far fewer are aware of the incredibly potent antioxidant power of Xanthones. Xanthones are natural chemical substances that have recently won high praise from numerous scientists and researchers. Xanthones have been studied for their medicinal potential, since they demonstrate a number of pharmaceutical properties.
The Research on Xanthones:
Xanthones have been the subject of intense research for several decades. They are found in a select number of rain forest plants, but nowhere are they found in more abundance that in the pericarp or rind, of the Mangosteen fruit. This smooth, purple covering that was ground with ancient mortars and used to heal infection turns out to be the mother lode of beneficial Xanthones.
The two most beneficial Xanthones found in the Mangosteen have been named Alpha Mangostin and Gamma Mangostin. When isolated and thoroughly tested by researchers, these two Xanthones have been found to carry a host of benefits.
According to professional journals such as Free Radical Research, Journal of Pharmacology, and the Indian Journal of Experimental Biology, these Xanthones have a remarkable effect on cardiovascular health; are naturally antibiotic, antiviral, and anti-inflammatory; and are some of the most powerful antioxidants to be found in nature.
|
|
|
PROVEN BENEFITS OF XANTHONES …YOU CAN FEEL
1.) Anti-fatigue
2.) Anti-obesity
3.) Anti-depression
4.) Anti-anxiety
5.) Anti-Alzheimer's
6.) Anti-arthritis
7.) Anti--periodontic (gum disease)
8.) Anti-allergenic
9.) Anti-seborrheic (skin disease)
10.) Anti-pyretic (anti-fever)
11.) Anti-Parkinsonism
12.) Anti-diarrhea
13.) Anti-neuralgia (nerve pain)
14.) Anti-vertigo (dizziness)
15.) Anti-glaucoma
16.) Anti-pain (for example, dental pain)
17.) Anti-inflammatory (cox-2 inhibitor; like Vioxx & Celebrex but without side effects)
18.) Anti-ulcer (for example, ulcers of stomach, mouth, small bowel, large bowel) |
Health Benefits of Mangosteen: What Doctors Are Saying
A growing number of health practitioners are using the Mangosteen in their clinical practice as first-line or adjunctive therapy to treat their patients.
Read what they are saying about the health benefits of Mangosteen...*
“Mangosteen... is able to reverse most of the ailments of modern man.”
“Mangosteen provides huge health benefits for every organ in our bodies.”
“... One of the great medical discoveries of all time.”
“... I started taking the juice myself to try it, and then decided to use it in my practice. Since then,
I have used Mangosteen juice for various medical conditions...”
“... Because of my healing experience, I started researching the Mangosteen fruit and read many studies from around the Pacific Rim. I started sharing it with my patients as a complement to traditional medications. Many patients have been able to taper their medications while
on the Mangosteen.” –
“The benefits Mangosteen offers to people are monumental, and I'm immensely grateful
I have discovered it for my clients.”
“... We treat a lot of cancer patients in our clinic... The majority... are Stage Four and beyond. In some cases, they have been given six to eight weeks to live. We often witness wonderful results. The Mangosteen juice has become one of the many weapons in our arsenal. It has
given them their lives back...”
References:
1. Sundaram B.M., et al. Antimicrobial activities of (Garcinia mangostana L.). Planta Med. 1983; 48:59-60.
2. Begum N., et al. Anti-ulcer and antimicrobial activities of gartanin, xanthone from (Garcinia mangostana L.). Linn. Bull Islam Med. 1982; 2:518-21.
3. Chairungsrilerd N., et al. Histaminergic and serotonergic receptor-blocking substances from the medicinal plant (Garcinia mangostana L.). Planta Med. 1996; 62:471-2.
4. Chairungsrilerd N., et al. Pharmacological properties of a-mangostin, a novel histamine H1 receptor antagonist. Eur J Pharmacol. 1996; 314:351-6.
5. Nakatani K., et al. Inhibition of cyclooxygenase and prostaglandin E2 synthesis by g-mangostin, a xanthone derivative in mangosteen, in C6 rat glioma cells. Biochem Pharmacol. 2002; 63:73-9.
6. Nakatani K., et al. Inhibitions of histamine release and prostaglandin E2 synthesis by mangosteen, a Thai medicinal plant. Biol Pharm Bull. 2002; 25:1137-41.
7. Iinuma M., et al. Antibacterial activity of xanthones from Guttiferaeous plants against methicillin - resistant Staphylococcus aureus. J Pharm Pharmacol. 1996; 48:861-5.
8. Mahabusarakam W., et al. Antimicrobial activities of chemical constituents from (Garcinia mangostana L.). Linn. J Sci Soc Thailand. 1986; 12:239-42.
9. Sindermsuk J, et al. Comparison of the efficiency in diarrhea treatment between the leaf of guava (Psidium guajava L.), and the fruit hull of mangosteen (Garcinia mangostana L.). Mahidol Univ J Pharm Sci. 1989; 16:32-5.
10. Suksamrarn S, et al. Antimycobacterial activity of prenylated xanthones from the fruit of (Garcinia mangostana L.). Chem Pharm Bull. 2003; 51:857-9.
11. Chomnawang M.T., et al. Antimicrobial effects of Thai medicinal plants against acne-inducing bacteria. J Ethnopharmacol. 2005; 101(1-3):330-3.
12. Fan CT, Su JD. Antioxidative mechanism of isolated components from methanol extract of fruit hulls of (Garcinia mangostana L.). J Chin Agric Chem Soc. 1997; 35:540-51.
13. Chen SX, et al. Active constituents against HIV-1 protease from (Garcinia mangostana L.). Planta Med. 1996; 62:381-2.
14. Matsumoto K, et al. Induction of apoptosis by xanthones from mangosteen in human leukemia cell lines. J Nat Prod. 2003; 66:1124-7.
15. Moongkarndi P., et al. Antiproliferation, antioxidation & induction of apoptosis by Garcinia mangostana (mangosteen) on SKBR3 human breast cancer cell line. J Ethnopharmacol. 2004; 90:161-6.
16. Lim-Sylianco C.Y., et al. Antimutagenic effects of expressions from eighteen medicinal plants. Philippine J Sci. 1986; 115;293-8.
17. Yoshikawa M., et al. [Antioxidant constituents from the fruit hulls of mangosteen (Garcinia mangostana L.) originating in Vietnam]. Yakugaku Zasshi. 1994; 114:129-
18. Chanarat P., et al. Immunopharmacological activity of polysaccharide from the pericap of mangosteen garcinia: Phagocytic intracellular killing activities. J Med Assoc Thai. 1997; 80(suppl.).
19. Williams P., et al. Mangostin inhibits the oxidative modification of human low density lipoprotein. Free Radical Res. 1995; 23:175-84.
|
Only your doctor can properly diagnose and treat any disease or disorder. Before starting the use of any nutritional supplement, it is important to consult with your doctor. The statements on this web site have not been evaluated by the U.S. Food Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. Information on the site is educational information only and does not warrant, imply or guarantee any result or cure.
|
|
|
|
|
| |
